Novel Antibiotic Combinations of Diverse Subclasses for Effective Suppression of Extensively Drug-Resistant Methicillin-Resistant Staphylococcus aureus (MRSA)

Table 1

List of antibiotics tested against the MRSA isolate (LR-2).

Antibiotic	Brand name	Manufacturer	Form	Potency	Final conc.
Cephalosprin
Cephradine (RAD)	Velosef	GlaxoSmithKline (GSK)	IV	1 g	10 mg/ml
Cefuroxime (CXM)	Zinacef	GlaxoSmithKline (GSK)	IV	1.5 g	10 mg/ml
Ceftazidime (CAZ)	Fortum	GlaxoSmithKline (GSK)	IV	500 mg	10 mg/ml
Cefotaxime (CTX)	Claforan	Sanofi-Aventis Pak Ltd.	IV	1 g	10 mg/ml
Ceftriaxone (CRO)	Rocephin	F.Hoffmann-La Roche Ltd.	Tablets	1 g	10 mg/ml
Cefepime (FEP)	Maxipime	GlaxoSmithKline (GSK)	IV	1 g	10 mg/ml
Aminoglycosides
Amikacin (AK)	Gracil	Sami Pharmaceticals (Pvt.) Ltd.	IV	500 mg/2 ml	10 mg/ml
Gentamycin (CN)	Genticyn	Ray Pharma (Pvt.) Ltd.	IV	80 mg/2 ml	10 mg/ml
Tobramycin (TOB)	Nebcin	AGP Limited	IV	80 mg/2 ml	10 mg/ml
Fosfomycin (FOS)	Monural	Zambon	Sachet	3 g	10 mg/ml
Fluoroquinolones
Ofloxacin (OFX)	Oflobid	Hilton Pharma (Pvt.) Ltd.	Tablets	200 mg	10 mg/ml
Levofloxacin (LVX)	Leflox	Getz Pharma	Tablets	500 mg	10 mg/ml
Sparfloxacin (SPX)	Sparaxin	Abbot Laboratories (Pak) Ltd.	Tablets	100 mg	10 mg/ml
Moxifloxacin (MOX)	Avelox	Bayer Pharma AG			10 mg/ml
Carbapenem
Meropenem (MEM)	Meronem	Pfizer Limited	IV	500nmg	10 mg/ml
Imipenem (IPM)	Tienam	Merck Sharp & Dohme Corp. (MSD)	IV	500 mg	10 mg/ml
Ampicillin + β-lactam Inhibitor
Amoxicillin/clavulanic acid (AUG)	Augmentin	GlaxoSmithKline (GSK)	Tablets	625 mg	10 mg/ml
Piperacillin/tazobactam (TZP)	Tanzo	Bosch Pharmaceuticals (Pvt.) Ltd	IV	4.5 g	10 mg/ml