In Vitro Modulator Effect of Total Extract from the Endophytic Paenibacillus polymyxa RNC-D in Leishmania (Leishmania) amazonensis and Macrophages

Table 4

NO concentration in the cells treated and not treated with Paenibacillus polymyxa RNC-D extract.

Group	24 h (µM)	48 h (µM)	72 h (µM)
Control	4.216 ± 0.1^NS	4.632 ± 0.2^NS	2.118 ± 0.5^NS
0.1 mg/mL	5.835 ± 1.5^NS	6.428 ± 1.7^NS	2.519 ± 0.6^NS
0.5 mg/mL	4.726 ± 0.5^NS	24.936 ±.5	17.411 ± 4.6
1 mg/mL	4.868 ± 1.2^NS	20.636 ± 6.0	17.353 ± 3.4
LPS-100 ng/mL	8.724 ± 2.5	108.385 ± 2.4	84.678 ± 4.7

and represent the significant difference between the treated group and the control group (no treatment). NS: without statistical difference.