Genotyping of Helicobacter pylori Virulence Genes cagA and vacA: Regional and National Study

Table 3

Association between virulence genes and endoscopic findings in H. pylori strains (no. = 60).

Virulence genes	vacA genotypes (No.)	Endoscopic findings (n = 60)
		PUD (30) No. (%)	value	Gastritis (25) No. (%)	value	GERD (15) No. (%)	value	Others (18) No. (%)	value
vacA+/cagA+	s1m1 (26)	10 (33.3%)	<0.001	12 (20%)	<0.001	8 (13.3%)	<0.001	6 (10%)	<0.001
	s1m2 (5)	5 (16.6%)		4 (6.6%)		2 (3.3%)		0 (0.0%)
	s2m2 (1)	1 (3.3%)		0 (0.0%)		1 (1.6%)		0 (0.0%)
vacA+/cagA−	s1m1 (1)	0 (0.0%)	0.392	1 (3.3%)	0.392	0 (0.0%)		0 (0.0%)
	s1m2 (2)	1 (3.3%)		1 (3.3%)		0 (0.0%)		0 (0.0%)
	s2m2 (2)	0 (0.0%)		2 (6.6%)		0 (0.0%)		0 (0.0%)
vacA−/cagA−		13 (23.3%)		5 (11.6%)		4 (1.6%)		12 (16.6%)

PUD: Peptic Ulcer Disease. GERD: Gastroesophageal Reflux Disease.