Research Article

Hepatitis C Virus Infection among HIV-Infected Patients Attending Dessie Referral Hospital, Northeastern Ethiopia

Table 2

Anti-HCV positivity in relation to HCV risk factors and sociodemographic factors among HIV-infected patients at Dessie Referral Hospital, Northeastern Ethiopia, 2018.

VariablesHCV antibodyCOR (95% CI) valueAOR (95%CI) value
Positive no. (%)Negative no. (%)

Knowledge of HCV causative agent
Yes3(3.2)90(96.8)1
No10(6.4)146(93.6)2.055 (0.551, 7.666)0.284NA

Knowledge of the mode of transmission
Yes1(2.0)49(98.0)1
No12(6.0)187(94.0)3.144 (0.399, 24.772)0.277NA

History of hospitalization
Yes10(13.2)66(86.8)8.586 (2.291, 32.177)0.00110.234 (2.049, 51.118)0.005
No3(1.7)170(98.3)1

Previous surgical history
Yes2(8.3)22(91.7)1.769 (0.368, 8.495)0.476NA
No11(4.9)214(95.1)1

History of skin disorder
Yes5(5.6)85(94.4)1.110 (0.352, 3.501)0.858NA
No8(5.0)151(95.0)1

History of circumcision
Yes7(5.1)131(94.9)0.935 (0.305, 2.867)0.907NA
No6(5.4)105(94.6)1

History of blood transfusion
Yes3(5.3)54(94.7)1.011 (0.269, 3.806)0.987NA
No10(5.2)182(94.8)1

History of unsafe sexual intercourse
Yes6(6.3)89(93.7)1.416 (0.461, 4.347)0.544NA
No7(4.5)147(95.5)1

History of tooth extraction
Yes4(17.4)19(82.6)5.076 (1.429, 18.034)0.0126.016 (1.137, 36.837)0.048
No9(4.0)217(96.0)1

Sharing of sharp material with friends
Yes1(7.1)13(92.9)1.429 (0.172, 11.853)0.741NA
No12(5.1)223(94.9)1

Smoking habit
Yes2(8.3)22(91.7)1.606 (0.336, 7.679)0.553NA
No13(5.8)212(94.2)1

Drinking habit
Yes3(4.9)58(95.1)0.921 (0.245, 3.460)0.903NA
No10(5.3)178(94.7)1

Liver disease
Yes3(25)9(75)7.567 (1.771, 32.323)0.00611.398 (1.275, 101.930)0.029
No10(4.2)227(95.8)1

Duration of HIV infection from diagnosis
>10 years12(6.9)161(93.1)5.590 (0.714, 43.786)0.1014.934 (0.463, 52.548)0.186
<10 years1(1.3)75(98.7)1

Duration of HIV treatment
>10 years8(11.6)61(88.4)3.905 (1.241, 34.546)0.0215.490 (1.341, 34.458)0.041
<10 years5(2.8)175(97.2)1

WHO clinical stage
I/II5(2.6)184(97.4)1
III/IV8(13.3)52(86.7)5.662 (1.777, 18.041)0.00312.768 (2.293, 71.106)0.004

CD4+ category, cells/mm3
≤2005(4.5)106(95.5)0.767 (0.244, 2.412)0.6490.559 (0.120, 2.598)0.458
>2008(5.8)130(94.2)1

Sex
Male10(8.4)109(91.6)3.884 (1.042, 14.471)0.0434.555 (0.842, 24.655)0.078
Female3(2.3)127(97.7)1

Age
≤50 years9(4.4)208(95.9)1
>50 years4(12.5)28(87.5)3.302 (0.953, 11.433)0.0599.070 (1.578, 52.117)0.013

Statistically significant at . AOR: adjusted odds ratio, COR: crude odds ratio, 1: reference group, 95% CI: 95% confidence interval, HCV: Hepatitis C Virus, HIV: Human Immunodeficiency Virus, NA: not applicable, WHO: World Health organization.