International Journal of Microbiology

Research Article

Detection of blaOXA-145, blaOXA-224, blaOXA-539, and blaOXA-675 Genes and Carbapenem-Hydrolyzing Class D β-Lactamases (CHDLs) in Clinical Isolates of Pseudomonas aeruginosa Collected from West of Iran, Hamadan

Table 3

Correlation between OXA genes, biofilm formation, separated clinical isolates, and antibiotic resistance in P. aeruginosa.


Biofilm	OXA genes
Biofilm	blaOXA-145	blaOXA-161	blaOXA-224	blaOXA-539	blaOXA-675	blaOXA-848

Strong	P = 0.009	P = 0.001	P = 0.008	P = 0.009	P = 0.039	P = 0.022
Moderate	P = 0.017	P = 0.050	P = 0.036	P = 0.002	P = 0.075	P = 0.033
Weak	P = 0.043	P = 0.003	P = 0.032	P = 0.017	P = 0.015	P = 0.048
Antibiotic resistance
CEF	P = 0.040	P = 0.029	P = 0.016	P = 0.048	P = 0.066	P = 0.043
PIP	P = 0.671	P = 0.371	P = 0.40	P = 0.11	P = 0.96	P = 0.115
GEN	P = 0.250	P = 0.089	P = 0.014	P = 0.097	P = 0.25	P = 0.01
AMK	P = 0.111	P = 0.089	P = 0.077	P = 0.091	P = 0.088	P = 0.049
NOR	P = 0.058	P = 0.060	P = 0.084	P = 0.12	P = 0.09	P = 0.049
CIP	P = 0.31	P = 0.11	P = 0.33	P = 0.47	P = 0.075	P = 0.082
CAZ	P = 0.085	P = 0.020	P = 0.009	P = 0.005	P = 0.066	P = 0.043
CTX	P = 0.072	P = 0.061	P = 0.049	P = 0.021	P = 0.013	P = 0.069
IMI	P = 0.049	P = 0.016	P = 0.055	P = 0.005	P = 0.009	P = 0.045
MER	P = 0.019	P = 0.062	P = 0.035	P = 0.015	P = 0.009	P = 0.45
ERT	P = 0.31	P = 0.11	P = 0.33	P = 0.47	P = 0.075	P = 0.082
FOX	P = 0.025	P = 0.015	P = 0.084	P = 0.001	P = 0.075	P = 0.033
CFX	P = 0.002	P = 0.001	P = 0.072	P = 0.050	P = 0.039	P = 0.044
MBL	P = 0.019	P = 0.020	P = 0.048	P = 0.053	P = 0.036	P = 0.050
KPC	P = 0.094	P = 0.31	P = 0.19	P = 0.020	P = 0.62	P = 0.27
MDR	P = 0.017	P = 0.039	P = 0.047	P = 0.050	P = 0.038	P = 0.019
XDR	P = 0.049	P = 0.046	P = 0.055	P = 0.025	P = 0.019	P = 0.065
Clinical specimens
Urine	P = 0.029	P = 0.036	P = 0.015	P = 0.077	P = 0.059	P = 0.045
Blood	P = 0.049	P = 0.016	P = 0.055	P = 0.012	P = 0.019	P = 0.016
Wound	P = 0.017	P = 0.022	P = 0.034	P = 0.019	P = 0.049	P = 0.011
Sputum	P = 0.087	P = 0.092	P = 0.096	P = 0.190	P = 0.130	P = 0.220
Body fluids	P = 0.120	P = 0.151	P = 0.192	P = 0.099	P = 0.101	P = 0.100