Angiotensin-Converting Enzyme-2 (ACE-2) with Interferon-Induced Transmembrane Protein-3 (IFITM-3) Genetic Variants and Interleukin-6 as Severity and Risk Predictors among COVID-19 Egyptian Population

Table 5

Comparison between IL-6 serum 1^st reading among the selected participants (n = 200) of both pandemic waves.

IL-6 1^streading (pg\ml)	Mild/moderate (n = 40)	Severe (n = 60)	Critical (n = 60)	Control (n = 40)
Min.–Max.	2.45–224.0	3.0–484.0	8.0–531.0	1.0–6.0	<0.001
Mean ± SD.	22.60 ± 39.97	80.38 ± 102.8	135.8 ± 126.0	3.63 ± 1.39
Median (IQR)	8.65 (5.0–18.0)	31.2 (16.0–116.0)	84.3 (35.0–200.0)	3.50 (3.0–5.0)
0	<0.001	<0.001	<0.001
Sig. bet. subgrps.	1, 2, 3 =

IQR: interquartile range SD: standard deviation. : value for comparing between the four studied groups. ₀: value for comparing between control and each other groups. ₁: value for comparing between mild/moderate and severe. ₂: value for comparing between mild/moderate and critical. ₃: value for comparing between severe and critical. Statistically significant at .