Angiotensin-Converting Enzyme-2 (ACE-2) with Interferon-Induced Transmembrane Protein-3 (IFITM-3) Genetic Variants and Interleukin-6 as Severity and Risk Predictors among COVID-19 Egyptian Population

Table 8

Univariate and multivariate logistic regression analyses for predictors of COVID-19 susceptibility: cases vs. controls (n = 160 vs. 40).

Parameters	Univariate		^#Multivariate
		OR (LL–UL 95% CI)		OR (LL–UL 95% CI)
ACE2 (rs2285666) (CT + TT)	<0.001	6.600 (2.996–14.541)	0.617	1.760 (0.192–16.148)
IFITM-3 (rs12252) (AG + GG)	<0.001	6.412 (2.912–14.116)	0.231	4.225 (0.399–44.725)
Comorbidities	<0.001	5.559 (2.659–11.620)	0.605	1.684 (0.233–12.167)
Age (years)	0.632	1.005 (0.983–1.028)
Female	1.000	1.000 (0.493–2.028)

OR: odds ratio. CI: confidence interval. LL: lower limit. UL: upper limit. ^#All variables with were included in the multivariate analysis. Statistically significant at .