Research Article
APOBEC3G Polymorphisms and Implications for a Population with Chronic Hepatitis B Virus in Burkina Faso
Table 2
APOBEC3G genotypic frequencies according to chronic HBsAg status.
| | SNPs | Genotypes | HBsAg positive n = 106 (%) | HBsAg negative n = 239 (%) | Crude OR | 95% CI | value |
| | rs6001417 | CC | 16 (15.10) | 64 (26.80) | 1 | — | — | | CG | 59 (55.70) | 114 (47.70) | 2.07 | 1.10–3.89 | 0.02 | | GG | 31 (29.24) | 61 (25.52) | 2.03 | 1.01–4.08 | 0.05 | | C | 91 | 242 | 1 | — | — | | G | 121 (57.07) | 236 (49.37) | 1.36 | 0.98–1.89 | 0.06 | | HWEa | 0.37 | 0.78 | — | — | — |
| | rs8177832 | AA | 26 (24.52) | 69 (28.90) | 1 | — | — | | AG | 59 (55.70) | 111 (46.44) | 1.41 | 0.81–2.45 | 0.22 | | GG | 21 (19.81) | 59 (24.70) | 0.94 | 0.48–1.85 | 0.87 | | A | 111 | 249 | 1 | — | — | | G | 101 (47.6) | 229 (47.91) | 0.99 | 0.72–1.37 | 0.95 | | HWEa | 0.49 | 0.56 | — | — | — |
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HBsAg: hepatitis B virus surface antigen; OR: odds ratio; CI: confidence interval; CC, CG, GG: genotypes of d variant rs6001417; AA, AG, GG: genotypes of variant rs8177832. Bold values highlight statistically significant values, i.e., p-values less or equal to 0.05.
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