International Journal of Nephrology

Research Article

Relationship between Angiotensin-Converting Enzyme Insertion/Deletion Gene Polymorphism and Susceptibility of Minimal Change Nephrotic Syndrome: A Meta-Analysis

Table 2

Meta analysis of the association of ACE I/D gene polymorphism with MCNS risk.
Genetic contrastsGroup and subgroupsStudies number test valueModelOR (95% CI)
D versus IOverall6.64Fixed1.39 ( ).007
Asian4.46Fixed1.38 ( ).01
Caucasian1—Fixed1.69 ( ).16
Africa1—Fixed0.85 ( ).81
DD versus (DI + II)Overall6.45Fixed1.46 ( ).04
Asian4.36Fixed1.60 ( ).02
Caucasian1—Fixed1.01 ( ).98
Africa1—Fixed0.35 ( ).49
II versus (DI + DD)Overall6.58Fixed0.65 ( ).03
Asian4.70Fixed0.73 ( ).12
Caucasian1—Fixed0.08 ( ).09
Africa1—Fixed0.62 ( ).76