The Effects of Helicobacter pylori Eradication on Proteinuria in Patients with Primary Glomerulonephritis

Table 2

Clinical and laboratory features of the patients before and after H. pylori eradication therapy.

	MN group (𝑛=19)	IgAN group (𝑛=10)	FSGS group (𝑛=4)	𝑃 value
Male/female	13/6	4/6	3/1	NS
Age (years)	45±13	39±12	37±11	NS
BMI (kg/m^2)	25.0±4.7	27.9±5.8	25.4±3.5	NS
Before therapy
Systolic BP (mmHg)	119±22	133±18	123±8	NS
Diastolic BP (mmHg)	76±13	78±10	83±10	NS
Hemoglobin (g/dL)	13.1±2.0	12.3±1.1	12.5±0.9	NS
Glucose (mg/dL)	92±13	87±13	92±14	NS
Creatinine (mg/dL)	0.98±0.29	1.21±0.41	1.60±0.50	0.011
T. protein	6.38±1.11	6.52±1.35	6.30±0.70	NS
Albumin (g/dL)	3.66±0.75	3.76±0.83	3.90±0.32	NS
Proteinuria (Up/C) (g/day)	2.42±3.24	2.12±1.63	1.80±1.32	NS
GFR (mL/min)	89±29	69±27	56±20	NS
T. cholesterol (mg/dL)	214±54	232±60	235±82	NS
Triglyceride (mg/dL)	179±149	196±138	223±165	NS
hs-CRP	2.66±3.20	4.10±3.72	7.15±8.28	NS
After therapy
Systolic BP (mmHg)	116±22	135±16	119±9	NS
Diastolic BP (mmHg)	74±13	85±12	80±8	NS
Hemoglobin (mg/dL)	12.9±1.8	12.2±1.3	12.7±1.2	NS
Creatinine (mg/dL)	1.01±0.32	1.15±0.42	1.78±0.59	0.005
T. protein (g/dL)	6.66±0.92	6.06±1.31	6.73±0.31	NS
Albumin (g/dL)	3.89±0.61	3.61±0.91	4.06±0.38	NS
Proteinuria (g/day)	1.26±1.73	1.58±1.59	1.91±1.21	NS
GFR (mL/min)	87±29	72±30	51±24	NS

AMN: membranous nephropathy, IgAN: IgA nephropathy, FSGS: focal segmental glomerulosclerosis, NS: not significant, GFR: glomerular filtration rate.