Estimated Visceral Adipose Tissue, but Not Body Mass Index, Is Associated with Reductions in Glomerular Filtration Rate Based on Cystatin C in the Early Stages of Chronic Kidney Disease

Table 2

Differences between the glomerular filtration rate estimated by the modification of diet in renal disease and glomerular filtration rate estimated by Larsson, Levey 2, and Levey 3 equations by gender.

Variables	Total; 𝑛=241	Male; 𝑛=58	Female; 𝑛=183	𝑃 value
GFR MDRD (mL/min/1.73 m^2)	89.6±19.5	89.5±61.2	89.6±20.1	0.780
GFR Larsson (mL/min/1.73 m^2)	100.3±23.3	91.1±20.5	103.2±23.4	<0.001
Dif.	−10.7±22.9	−1.6±18.2	−13.6±23.4
𝑃 value	<0.001	0.503	<0.001
GFR Levey 2 (mL/min/1.73 m^2)	89.1±19.5	87.3±19.1	89.6±19.6	0.608
Dif.	0.5±20.2	2.2±17.6	−0.0±21.0
𝑃 value	0.685	0.379	0.963
GFR Levey 3 (mL/min/1.73 m^2)	89.1±16.7	86.7±16.6	89.9±16.8	0.265
Dif.	0.5±11.7	2.8±10.7	−0.2±11.9
𝑃 value	0.683	0.172	0.206

GFR: glomerular filtration rate (mL/min/1.73 m²); MDRD: modification of diet in renal disease equation; Larsson: equation with cystatin C and without age and gender adjustment or based only on cystatin C; Levey 2: equation with cystatin C and age and gender adjustment; Levey 3: equation with cystatin C, creatinine, age, and gender adjustment; Dif.: difference between the GFR estimated by MDRD and the other equations. Data are expressed as mean ± SD.