Single Nucleotide Polymorphisms in Pediatric Idiopathic Nephrotic Syndrome

Table 6

Comparison of haplotype distributions of the MDR1 loci in patients and controls as well as in patients with less than 5 relapses and patients with five or more relapses. Variants in order rs1128503, rs2032582, and rs1045642. values lower than 0.05 are marked with .

Haplotype	Patients ()		Controls ()		OR (95% CI)
		%		%
CTC	69	42.2	46	23.4	0.42 (0.27–0.66)	0.002
TGT	45	27.5	36	18.6	0.60 (0.36–0.98)	0.0412
TTC	13	8.1	31	15.6	2.18 (1.10–4.33)	0.0254
CGC	7	4.5	25	12.6	3.28 (1.38–7.79)	0.0072
TGC	11	6.5	20	10.0	1.58 (0.73–3.40)	0.242
CGT	7	4.2	15	7.8	1.86 (0.74–4.67)	0.1877
TTT	2	1.3	15	7.7	6.71 (1.51–29.80)	0.0123
Other	9	5.7	8	4.3	0.73 (0.28–1.94)	0.5425
Haplotype	Relapses <5 ()		Relapses >5 ()		OR (95% CI)
		%		%
CTC	42	40.6	28	55.3	1.88 (0.95–3.71)	0.07
TGT	32	30.4	16	31.4	1.06 (0.51–2.91)	0.88
TGC	10	9.5	1	2.4	0.19 (0.02–1.54)	0.1205
TTC	6	6.2	2	4.2	0.68 (0.13–3.50)	0.64
CGT	2	2.0	2	4.0	2.13 (0.29–15.54)	0.4578
CTT	3	3.2	1	2.6	0.69 (0.07–6.78)	0.7479
Other	8	8.1	0	0.0	0.11 (0.01–1.99)	0.1359