Transforming Growth Factor-β Protects against Inflammation-Related Atherosclerosis in South African CKD Patients

Table 3

Multiple linear regression analysis of determinants of serum TGF-β1 levels.

Variables	Unstandardized coefficients (β)	Standardized coefficients (Beta)	95% Confidence interval	P value
CIMT	− 81439.078	− 0.593	− 107604.8 – −55273.3	< 0.001
Creatinine	− 3.111	− 0.095	− 8.484 – 2.262	0.254
sCD14	0.000	– 0.006	– 0.005 – 0.005	0.965
LBP	– 0.026	– 0.096	– 0.082 – 0.031	0.374
MABP	– 122.815	– 0.174	– 226.892 – – 18.739	0.021
Albumin	304.912	0.095	– 227.427 – – 837.251	0.259
MCP-1	258.890	0.181	– 13.286 – 531.066	0.062
Hs-CRP	– 230.671	– 0.011	– 3758.684 – 3297.342	0.897

CIMT, carotid intima media thickness; MABP; mean arterial blood pressure; sCD14, serum CD14; LBP, lipopolysaccharide binding protein; MCP-1, monocyte chemoattractant protein-1; Hs-CRP, high sensitivity C-reactive protein.