Relation of Wnt Signaling Pathway Inhibitors (Sclerostin and Dickkopf-1) to Left Ventricular Mass Index in Maintenance Hemodialysis Patients

Table 4

Correlation between LVM and LVM/BSA and some demographic and laboratory parameters among the studied subgroups.

	LVM		LVMI
	r		r
S. sclerostin (ng/ml)	−0.329	0.010	−0.257	0.046
S. Dkk-1 (pg/dl)	−0.427	0.001	−0.324	0.012
Age (years)	0.409	0.001	0.352	0.007
BMI	0.219	0.085	−0.199	0.118
BSA	0.278	0.027	−0.305	0.015
HD_duration	−0.153	0.264	0.015	0.979
Gender	−0.112	0.380	0.153	0.232
HTN	0.300	0.019	0.247	0.054
HB (gm/dl)	−0.245	0.057	−0.299	0.019
S. albumin (gm/dl)	−0.229	0.076	−0.294	0.021
Syst_BP (mmhg)	0.243	0.059	0.249	0.053
Diast BP (mmhg)	0.251	0.051	0.211	0.103
S. cholesterol	−0.126	0.334	−0.205	0.112
S. TG (mg/dl)	−0.024	0.855	−0.179	0.166
S. HDL (mg/dl)	−0.268	0.036	−0.161	0.214
S. LDL (mg/dl)	−0.076	0.563	−0.158	0.225
AVC	0.417	0.001	0.464	< 0.001
MVC	0.297	0.02	0.360	0.004
Mid_arm_circ (cm)	0.067	0.609	−0.423	0.001
Waist_circ (cm)	0.204	0.115	−0.128	0.326
Dry_weight (kg)	0.282	0.028	−0.286	0.026
Kt/V	−0.046	0.723	0.183	0.158
S. Ca (mg/dl)	−0.085	0.514	−0.074	0.573
S. PO4 (mg/dl)	0.242	0.060	−0.028	0.831
iPTH (pg/dl)	0.023	0.787	−0.035	0.861

Spearman’s correlation used. Significant at ; highly significant at . LVM: left ventricular mass; LVM/BSA: left ventricular mass/body surface area; S. Dkk-1: serum Dickkopf-1; BMI: body mass index; BSA: body surface area; HD: hemodialysis; HTN: hypertension; HB (gm/dl): hemoglobin concentration (gram/deciliter); Syst_BP: systolic blood pressure; Diast BP: diastolic blood pressure; mmhg: millimeter Mercury; S. TG; serum triglyceride; S. HDL: serum high-density lipoprotein; S. LDL: serum low-density lipoprotein; AVC: aortic valve calcification; MVC: mitral valve calcification; circ: circumference; Kt/V: kinetic time/volume; S. Ca: serum calcium; S. PO₄: serum phosphorus; iPTH: intact parathyroid hormone; mg/dl: milligram/deciliter; pg/dl: picogram/deciliter; ng/dl: nanogram/deciliter.