Anti-Factor H Antibodies in Egyptian Children with Hemolytic Uremic Syndrome
Table 1
Demographic features and clinical findings in HUS patients.
Parameter
Typical HUS (n = 22)
Anti-FH-positive aHUS (n = 12)
Anti-FH-negative aHUS (n = 16)
Sex/males
12 (54.5%)
10 (83.3%)
6 (37.5%)
p value
Age (years)
1.95 ± 1.6
7.7 ± 3
4.3 ± 4
Consanguinity
2 (9.1%)
4 (33.3%)
3 (18.7%)
Prodromes
Diarrhea
22 (100%)
5 (41.6%)
10 (62.6%)
Fever
18 (81.8%)
6 (50%)
9 (56.3%)
Vomiting
20 (90.9%)
10 (83.3%)
12 (75%)
Respiratory infection
2 (9.1%)
2 (16.7%)
4 (25%)
Clinical symptoms
Oligo/anuria
22 (100%)
12 (100%)
16 (100%)
Hypertension
3 (13.6%)
2 (16.7%)
4 (25%)
Generalized edema
15 (68.2%)
7 (58.3%)
13 (81.2%)
Jaundice
3 (13.6%)
4 (33.3%)
3 (18.8%)
CNS affection
11 (50%)
5 (41.7%)
9 (56.3%)
Data are presented as the number of patients with the percentage in parentheses. Bold values are significant at . Analysis was done using chi-square test.
