Immunohistochemical Expression of FOXP3+ Regulatory T Cells in Proteinuric Primary Glomerulopathies

Table 1

Demographic, clinical, and laboratory patient characteristics.

	Total (Ν = 71)	IgAN (Ν = 28)	FSGS (Ν = 22)	MGN (Ν = 21)	value
Age (years)	48 ± 17	47 ± 14	42 ± 20a	56 ± 13a	a: 0.015
Gender (male, %)	63	50	68	76	ns
CKD-EPI eGFR (ml/min/1.73 m^2)	61 ± 32	59 ± 29	55 ± 31	70 ± 35	ns
Proteinuria (g/day)	4.5 ± 3.6	2.0 ± 1.9a,b	5.3 ± 4.2a	6.7 ± 2.8b	a: 0.001; b: <0.001
Nephrotic syndrome (%)	52	20	60	81	a: 0.001; b: <0.001
Arterial hypertension (%)	37	29	41	43	ns
Glomerular hematuria (%)	75	9βa,b	55a	71b	a: 0.002; b: 0.006

Note. Data are presented as mean value ± standard deviation or as percentage. FSGS: focal segmental glomerulosclerosis, IgAN: IgA nephropathy, CKD-EPI eGFR: glomerular filtration rate estimated with the CKD-EPI equation, MGN: membranous glomerulopathy, and ns: not significant.