Immunohistochemical Expression of FOXP3+ Regulatory T Cells in Proteinuric Primary Glomerulopathies

Table 5

Association between high FOXP3+/CD4+ ratio in the interstitial tissue (above average value: 0.185) with renal function level and proteinuria at biopsy using multivariable logistic regression.

	CKD-EPI eGFR ≥60 ml/min/1.73 m^2			Proteinuria ≥3.5 g/day
	OR	95% CI	value	OR	95% CI	value
FOXP3+/CD4+ ratio in the interstitial tissue
Low (<0.185)	1			1
High (>0.185)	4.80	1.29–17.91	0.019	0.93	0.29–3.00	0.902

Note. The final multivariable model was adjusted for the following confounding factors: age, gender, and interstitial fibrosis. CI: confidence interval, CKD-EPI eGFR: glomerular filtration rate estimated with the CKD-EPI equation, and OR: odds ratio.