Research Article
Blind Spot in the Radar of MEST-C Score: Type and Severity of Tubulointerstitial Nephritis in IgA Nephropathy
Table 4
Relationship between MEST-C score and type of tubulointerstitial inflammation.
| Clinicopathological parameters | Type of tubulointerstitial inflammation | value | Absent | Acute | Acute and chronic | Chronic |
| Age | 0–20 | 3 | 0 | 6 | 33 | 0.49 | 21–40 | 20 | 3 | 18 | 116 | 41–60 | 1 | 1 | 3 | 39 | 61–80 | 0 | 0 | 0 | 4 |
| Gender | Male | 13 | 2 | 19 | 138 | 0.27 | Female | 11 | 2 | 8 | 54 |
| Mesangial hypercellularity | M0 | 3 | 0 | 3 | 3 | 0.008 | M1 | 21 | 4 | 24 | 189 |
| Endocapillary hypercellularity | E0 | 20 | 2 | 10 | 94 | ≤0.001 | E1 | 4 | 2 | 17 | 98 |
| Segmental glomerulosclerosis | S0 | 6 | 0 | 3 | 18 | 0.168 | S1 | 18 | 4 | 24 | 174 |
| Tubular atrophy and interstitial fibrosis | T0 | 24 | 4 | 12 | 83 | ≤0.001 | T1 | 0 | 0 | 15 | 109 |
| Crescents (C) score | C0 | 24 | 3 | 15 | 126 | 0.003 | C1 | 0 | 0 | 9 | 50 | C2 | 0 | 1 | 3 | 16 |
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Total cases (n) = 247. Bold p values are statistically significant.
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