Blind Spot in the Radar of MEST-C Score: Type and Severity of Tubulointerstitial Nephritis in IgA Nephropathy

Table 5

Relationship between MEST-C score and the degree of tubulointerstitial inflammation.

		Degree of tubulointerstitial inflammation				value
		Absent	Mild	Moderate	Severe
Age	0–20	3	15	22	2	0.77
	21–40	20	55	75	7
	41–60	1	18	23	2
	61–80	0	2	2	0
Gender	Male	13	58	96	5	0.09
	Female	11	32	26	6
Mesangial hypercellularity	M0	3	5	1	0	0.023
	M1	21	85	121	11
Endocapillary hypercellularity	E0	20	53	48	5	≤0.001
	E1	4	37	74	6
Segmental glomerulosclerosis	S0	6	11	9	1	0.08
	S1	18	79	113	10
Tubular atrophy and interstitial fibrosis	T0	24	67	31	1	≤0.001
	T1	0	23	91	10
Crescents (C) score	C0	24	74	65	5	≤0.001
	C1	0	14	40	5
	C2	0	2	17	1

Total cases (n) = 247. Bold values are statistically significant.