Zinc Acetate Hydrate Supplementation versus Polaprezinc Supplementation for Improving Hypozincemia in Hemodialysis Patients: A Randomized Clinical Trial
Table 1
Comparison of baseline patient characteristics by groups.
ZAH group
PPZ group
value
Number of patients
37
38
—
Agea (years)
74.7
(12.8)
72.6
(13.0)
0.452
HD vintagea (years)
7.2
(5.4)
7.5
(5.7)
0.860
Male sexb
28
(75.7%)
27
(71.1%)
0.651
Primary diseaseb
0.686
Chronic glomerulonephritis n (%)
15
(40.5%)
14
(36.8%)
Diabetic nephropathy n (%)
16
(43.2%)
12
(31.6%)
Other, n (%)
6
(16.3%)
12
(31.6%)
Serum zinca (μg/dL)
52.3
(4.9)
52.4
(5.2)
0.903
Serum coppera (μg/dL)
89.1
(15.3)
93.5
(17.0)
0.396
Alkaline phosphatasea (U/L)
84.8
(30.2)
83.5
(34.1)
0.611
ALTa (U/L)
11.3
(5.1)
12.3
(5.7)
0.517
ASTa (U/L)
13.4
(4.4)
14.8
(9.4)
0.983
LDHa (U/L)
182.3
(37.2)
176.5
(43.9)
0.474
Total bilirubina (mg/dL)
0.37
(0.12)
0.37
(0.12)
0.772
Serum calciuma (mg/dL)
8.67
(0.56)
8.79
(0.65)
0.176
Serum creatininea (mg/dL)
9.11
(2.51)
9.69
(2.62)
0.539
Serum chlorinea (mEq/L)
101.8
(3.7)
102.3
(3.4)
0.516
Serum phosphatea (mg/dL)
5.3
(1.0)
5.5
(1.4)
0.592
Serum sodiuma (mEq/L)
139.2
(3.1)
138.5
(3.4)
0.465
Serum potassiuma (mEq/L)
4.5
(0.6)
4.5
(0.6)
0.874
Hemoglobina (g/dL)
11.3
(1.1)
11.2
(1.1)
0.286
Ferritina (ng/mL)
184.6
(130.9)
171.3
(118.9)
0.798
TSATa (%)
25.6
(10.7)
27.5
(17.1)
0.567
Glucosea (mg/dL)
155.4
(53.8)
141.1
(60.8)
0.075
LDL-cholesterola (mg/dL)
82.3
(18.7)
83.5
(20.1)
0.715
CRPa (mg/dL)
0.99
(1.98)
0.80
(1.20)
0.824
Total cholesterola (mg/dL)
141.6
(23.2)
151.8
(25.4)
0.063
Total proteina (g/dL)
6.1
(0.5)
6.3
(0.5)
0.307
Serum albumina (g/dL)
3.38
(0.26)
3.39
(0.32)
0.932
Transthyretina (mg/dL)
24.7
(5.5)
23.9
(5.5)
0.481
Urea nitrogena (mg/dL)
57.9
(13.1)
58.5
(14.0)
0.849
BNPa (pg/mL)
299.1
(241.5)
329.4
(514.0)
0.322
Treat timea (hours)
4.7
(0.6)
4.8
(0.6)
0.751
Dry body weighta (kg)
57.9
(11.3)
56.5
(9.0)
0.656
Systolic blood pressurea (mmHg)
149.9
(21.7)
150.4
(22.7)
0.870
Diastolic blood pressurea (mmHg)
80.5
(15.1)
82.0
(12.6)
0.508
aWilcoxon test. bχ2 test. Data are presented as n (%) or as the mean (SD). ALT, alkaline aminotransferase; AST, aspartate aminotransferase; BNP, human brain natriuretic peptide; CRP, C-reactive protein; LDH, lactate dehydrogenase; TSAT, transferrin saturation.
