Critically Ill Patients with Renal Hyperfiltration: Optimizing Antibiotic Dose

Figure 4

Correlation of the pharmacodynamics of an antimicrobial agent in terms of concentration vs time. C_max/MIC: maximum concentration rate (C_max) by MIC; T > MIC: time T that the antibiotic concentration remains above the minimum inhibitory concentration (MIC); MIC/AUC: ratio of the area under the curve (AUC) of concentration versus time above the MIC. Adapted from Freitas et al. [10].