The Effect of Amifostine on Submandibular Gland Histology after Radiation

Table 3

Histological variable analysis.

Parameter	N	Q1	Median	Q3	Cuzick’s 𝑃 value
Fatty replacement					0.82
Amifostine	5	1	2	3
Partial-amifostine	9	2	3	3
No-amifostine	10	1	2	3
Lobular architecture					0.57
Amifostine	5	0	0	0
Partial-amifostine	9	0	0	1
No-amifostine	10	0	0	0
Interstitial fibrosis					0.26
Amifostine	5	2	2	2
Partial-amifostine	9	2	2	2
No-amifostine	10	0	2	2
Ductal degeneration					0.19
Amifostine	5	0	2	2
Partial-amifostine	9	0	0	0
No-amifostine	10	0	0	0
Inflammatory component (diffuse)					0.55
Amifostine	5	1	2	2
Partial-amifostine	9	0	1	2
No-amifostine	10	1	2	2
Inflammatory component (focal)					0.94
Amifostine	5	0	0	2
Partial-amifostine	9	0	0	1
No-amifostine	10	0	0	2
Acinar degeneration					0.35
Amifostine	5	3	3	3
Partial-amifostine	9	2	3	3
No-amifostine	10	2	2.5	3