International Journal of Pediatrics

Clinical Study

T-Lymphocyte Subsets in Apparently Healthy Nigerian Children

Table 1

Total white cell count, total lymphocytes count, subsets, and percentages for healthy children by age group.


Phenotype (cells )	Age group				Total
Phenotype (cells )	0–28 days	29 days– years	1–5 years	6–12 years	Total

TWCC	= 61 (22.6)	= 62 (23.0)	= 74 (27.4)	= 73 (27.0)	= 270 (100.0)
Mean (SD)	11.16 (3.60)	9.25 (3.18)	7.85 (2.26)	6.39 (2.13)	8.53 (3.29)
50th (5th, 95th) centiles	10.70 (5.73, 17.38)	8.95 (4.50, 16.01)	7.65 (4.75, 12.00)	6.20 (2.50, 10.43)	8.10 (4.36, 14.39)

TLC	= 61 (22.6)	= 62 (23.0)	= 74 (27.4)	= 73 (27.0)	= 270 (100.0)
Mean (SD)	5.08 (2.02)	6.26 (2.28)	4.06 (1.34)	3.17 (1.05)	4.56 (2.04)
50th (5th, 95th) centiles	4.85 (2.52, 8.70)	6.10 (2.88, 10.75)	3.95 (2.20, 6.15)	3.10 (1.40, 4.90)	4.10 (2.20, 8.65)

% lymphocyte count	= 61 (22.6)	= 62 (23.0)	= 74 (27.4)	= 73 (27.0)	= 270 (100.0)
Mean (SD)	47.23 (15.05)	67.61 (8.21)	51.90 (8.18)	50.76 (10.10)	54.10 (12.98)
50th (5th, 95th) centiles	46.40 (25.08, 69.88)	67.7 (55.24, 82.14)	51.90 (37.08, 64.75)	50.00 (33.81, 70.46)	54.10 (31.32, 74.88)

CD3	= 57 (21.8)	= 62 (23.7)	= 74 (28.2)	= 69 (26.3)	= 262 (100.0)
Mean (SD)	2.59 (0.73)	2.44 (0.81)	2.19 (0.69)	1.94 (0.66)	2.27 (0.76)
50th (5th, 95th) centiles	2.50 (1.44, 3.50)	2.37 (0.98, 3.50)	2.18 (1.14, 3.49)	1.85 (0.79, 3.32)	2.21 (1.04, 3.50)

CD4	= 57 (21.8)	= 62 (23.7)	= 74 (28.2)	= 69 (26.3)	= 262 (100.0)
Mean (SD)	1.66 (0.35)	1.49 (0.44)	1.16 (0.43)	1.08 (0.42)	1.33 (0.47)
50th (5th, 95th) centiles	1.76 (1.11, 2.00)	1.53 (0.64, 2.00)	1.05 (0.57, 2.00)	1.00 (0.39, 1.85)	1.28 (0.58, 2.00)

CD4 percentage	= 55 (21.7)	= 58 (22.8)	= 74 (29.1)	= 67 (26.4)	= 254 (100.0)
Mean (SD)	35.93 (9.03)	26.58 (6.23)	29.19 (8.17)	33.81 (8.10)	31.27 (8.67)
50th (5th, 95th) centiles	35.71(22.65, 50.14)	26.06 (18.50, 43.94)	28.26 (17.27, 44.95)	34.33 (19.47, 48.78)	30.09 (18.96, 46.66)

CD8 count	= 57 (21.8)	= 62 (23.7)	= 74 (28.2)	= 69 (26.3)	= 262 (100.0)
Mean (SD)	0.74 (0.30)	0.80 (0.42)	0.84 (0.38)	0.67 (0.31)	0.76 (0.36)
50th (5th, 95th) centiles	0.72 (0.32, 1.23)	0.72 (0.21, 1.61)	0.77 (0.35, 1.61)	0.63 (0.19, 1.44)	0.69 (0.32, 1.57)

CD8 Percent	= 55 (21.7)	= 58 (22.8)	= 74 (29.1)	= 67 (26.4)	= 254 (100.0)
Mean (SD)	15.07 (4.51)	13.47 (4.37)	20.74 (6.51)	20.99 (6.60)	17.92 (6.58)
50th (5th, 95th) centiles	14.32 (9.20, 24.35)	13.67 (7.22, 21.05)	20.74 (10.17, 30.25)	20.70 (11.87, 30.32)	17.20 (8.70, 29.25)

CD4 : CD8	= 57 (21.8)	= 62 (23.7)	= 74 (28.2)	= 69 (26.3)	= 262 (100.0)
Mean (SD)	2.54 (1.06)	2.24 (1.15)	1.57 (0.70)	1.72 (0.62)	1.98 (0.97)
50th (5th, 95th) centiles	2.36 (1.33, 4.18)	2.10 (1.07, 3.51)	1.49 (0.69, 2.89)	1.68 (0.82, 2.89)	1.81 (0.84, 3.51)

Note: Subjects with missing values were excluded, TWCC: Total White Cell Count, TLC: Total Lymphocyte Count.