Effects of Undernutrition and Predictors on the Survival Status of HIV-Positive Children after Started Antiretroviral Therapy (ART) in Northwest Ethiopia
Table 4
Bivariable and multivariate Cox regression for predictors of mortality of undernourished HIV-positive children among selected health facility of Northwest Ethiopia 2009-2020.
Variables
Categories
Survival status
CHR (95% CI)
AHR (95% CI)
Died
Censored
Sex
Male
35
302
1
1
Female
56
328
1.3 (0.88, 2.07)
1.7 (0.70, 1.70)
Age
≤60 months
29
49
2.8 (1.70, 4.60)
1.7 (0.79, 3.20)
61–120 months
23
231
1.2 (0.79, 2.11)
2.5 (0.93, 4.50)
≥121 months
38
351
1
1
Residence
Urban
61
449
1.16 (0.73, 1.87)
1.12 (0.7, 1.85)
Rural
29
182
1
1
CD4 count
Below threshold
70
238
3.12 (1.90, 7.20)
1.6 (1.19, 7.85)
Above threshold
20
393
1
1
WHO stage
Stages I and II
8
435
1
1
Stages III and IV
82
196
10.9 (5.20, 22.70)
4.5 (2.80, 8.40)
Adherence
Optimal adherence
21
489
1
1
Suboptimal adherence
69
142
6.3 (3.80, 10.30)
1.8 (0.60, 3.60)
Dietary counseling
Yes
44
421
1
1
No
46
210
1.8 (1.50, 2.50)
1.9 (0.50, 1.50)
Disclosure status
Yes
54
104
3.3 (2.30, 5.10)
1.7 (0.59, 2.8)
No
36
527
1
1
Duration of follow-up
≤36 months
6
217
1
1
37–72 months
19
276
2.1 (0.90, 5.10)
2.1 (0.70, 5.70)
>72 months
65
138
7.1 (3.10, 16.30)
2.6 (0.80, 3.60)
Wasting
Normal
70
461
1
1
Moderate (WHZ or )
18
101
9.6 (1.28, 12.6)
0.8 (0.18, 4.30)
Severe (WHZ or )
2
69
7.8 (1.80, 16.30)
1.07 (0.50, 1.90)
Underweight
Normal
34
457
1
1
Moderate ()
18
126
1.6 (0.91, 2.91)
0.6 (0.30, 1.17)
Severe ()
38
48
2.9 (1.80, 4.82)
1.2 (0.60, 2.1)
Stunting
Normal
18
410
1
1
Moderate ()
29
125
5.6 (2.50, 8.40)
1.6 (0.80, 3.20)
Severe ()
43
96
4.6 (3.20, 9.90)
2.9 (1.80, 6.40)
MUAC
≤11.5 cm
56
214
4.5 (2.10, 6.10)
1.5 (0.60, 4.20)
>11.5 cm
34
417
1
1
CPT
Yes
17
402
1
1
No
73
229
2.5 (1.60, 7.60)
1.2 (0.43, 4.50)
SAM admission history
Yes
37
91
2.8 (1.80, 4.30)
1.7 (0.60, 2.90)
No
53
540
1
1
CHR = crude hazard ratio; AHR = adjusted hazard ratio; CI = confidence interval; 1 = reference category. Significant predictors variables on final the multivariable models at .
