The Effectiveness of Synbiotic on the Improvement of Clinical Symptoms in Children with Eosinophilic Esophagitis
Table 1
Comparison of severity scores pre- and postintervention between groups.
Case ()
Control ()
value
Median (IQR)#
[Min, Max]
Median (IQR)
[Min, Max]
Total score of severity
Before
14 (6.5)
[6, 28]
12 (6.5)
[6, 14]
0.309
After
2 (1.5)
[0, 4]
4 (2.0)
[0, 8]
0.221
value
0.002
0.001
Chest pain
Before
0 (0.0)
[0, 50]
[0, 25]
0.655
After
0 (0.0)
[0, 25]
0 (0.0)
[0, 0]
0.020
value
0.317
0.317
Nausea
Before
25 (50.0)
[0, 75]
50 (50.0)
[0, 75]
0.981
After
0 (0.0)
[0, 25]
12.5 (25.0)
[0, 25]
0.143
value
0.026
0.002
Vomiting
Before
12.5 (56.25)
[0, 100]
25 (50.0)
[0, 75]
0.280
After
0 (0.0)
[0, 0]
0 (0.0)
[0, 25]
0.999
value
0.042
0.004
Stomach ache
Before
0 (50.0)
[0, 75]
25 (31.25)
[0, 75]
0.280
After
0 (25.0)
[0, 25]
0 (25.0)
[0, 25]
0.999
value
0.098
0.001
Poor appetite
Before
50 (50.0)
[0, 75]
25 (50.0)
[0, 50]
0.038
After
0 (0.0)
[0, 25]
0 (25.0)
[0, 25]
0.037
value
0.004
0.008
Dysphagia
Before
0 (25.0)
[0, 75]
0 (6.25)
[0, 50]
0.320
After
0 (0.0)
[0, 0]
0 (0.0)
[0, 0]
0.999
value
0.039
0.059
Reflux
Before
0 (0.0)
[0, 25]
0 (25)
[0, 50]
0.255
After
0 (0.0)
[0, 0]
0 (0.0)
[0, 0]
0.999
value
0.317
0.038
Sore throat
Before
0 (0.0)
[0, 0]
0 (0.0)
[0, 50]
0.201
After
0 (0.0)
[0, 0]
0 (0.0)
[0, 0]
0.999
value
0.317
0.999
Need to drink fluids
Before
0 (25.0)
[0, 100]
0 (0.0)
[0, 50]
0.465
After
0 (0.0)
[0, 0]
0 (0.0)
[0, 25]
0.078
value
0.109
0.157
Resulted from the comparison of between-group (case-control) by independent -test. Resulted from the comparison of within-group (before-after) by paired -test. #Interquartile range (IQR).