Comparison of Airway Pressure Release Ventilation to High-Frequency Oscillatory Ventilation in Neonates with Refractory Respiratory Failure

Table 1

Infants failing SIMV rescued with APRV.

	SIMV at failure ()	APRV at rescue ()	value
Peak pressures (cmH2O)	26.2 ± 4.5	23.7 ± 3.7	<0.001
Measured PEEP (cmH2O)	7.4 ± 1.9	6.3 ± 1.9	<0.001
Ventilator rate	45.7 ± 11.6	51.9 ± 10.3	0.001
Ventilator MPaw (cmH2O)	14.3 ± 3.2	18.0 ± 3.2	<0.001
FiO2 (%)	73.0 ± 27	69.5 ± 27	0.13
pH^†	7.30 ± 0.12	7.36 ± 0.12	<0.001
pCO2^† (mmHg)	78.9 ± 24.6	59.0 ± 10.1	<0.001
Base excess^†	7.4 ± 8.0	7.0 ± 8.4	0.55

^†Blood gas values for SIMV at the time of failure and for APRV at the time of the second blood gas after rescue. PEEP: positive end-expiratory pressure; M_Paw: mean airway pressure; FiO₂: fractional inspired oxygen; pCO₂: partial pressure of carbon dioxide. Data expressed as .