International Journal of Pediatrics

Research Article

Comparison of Airway Pressure Release Ventilation to High-Frequency Oscillatory Ventilation in Neonates with Refractory Respiratory Failure

Table 2

Infants grouped by corrected gestational age (CGA) at failure (28-37 weeks).


		APRV () rescue	HFOV () rescue	value

Patient characteristics	GA at birth (wk)	26.7 (25.3-28.0)	28.9 (27.8-30.3)	0.24
	CGA at failure (wk)	33.4 (32.3-34.1)	32.7 (29.8-34.3)	0.20
	Birth weight (g)			0.51
	Weight at failure (g)			0.58
	CGA at discharge (wk)	44.0 (32.4-46.6)	39.9 (38.6-41.8)	0.99
	Pneumothorax (%)	0 (0)	2 (10)	0.31
	Survival (%)	7 (78)	16 (84)	0.68

Patient status at failure of SIMV	PIP (cmH₂O)			0.01
	Measured PEEP (cmH₂O)			0.02
	Ventilator rate			0.46
	Ventilator M_Paw (cmH₂O)			0.01
	pH			0.03
	pCO₂ (mmHg)			0.44
	Base excess			0.005
	FiO₂ (%)			0.89
	Heart rate			0.28
	Respiratory rate			0.76
	BP MAP (mmHg)			0.02

Patient status at rescue^†	Ventilator M_Paw (cmH₂O)			0.02
	pH			0.05
	pCO₂ (mmHg)			0.44
	Base excess			0.06
	FiO₂ (%)			0.86
	Heart rate			0.53
	BP MAP (mmHg)			0.03

^†Values for both APRV and HFOV at the time of the second blood gas after rescue. PIP: peak inspiratory pressure; PEEP: positive end-expiratory pressure; pCO₂: partial pressure of carbon dioxide, FiO₂: fractional inspired oxygen, BP MAP: blood pressure mean arterial pressure; M_Paw: mean airway pressure. Data expressed as median with interquartile range () or .