Comparison of Airway Pressure Release Ventilation to High-Frequency Oscillatory Ventilation in Neonates with Refractory Respiratory Failure
Table 3
Infants grouped by corrected gestational age (CGA) at failure (>37 weeks).
APRV () rescue
HFOV () rescue
value
Patient characteristics
GA at birth (wk)
33.6 (27.0-38.0)
37.6 (34.1-38.9)
0.04
CGA at failure (wk)
40.9 (39.9-43.6)
39.0 (38.1-40.1)
<0.001
Birth weight (g)
0.05
Weight at failure (g)
0.004
CGA at discharge (wk)
45.7 (39.4-50.0)
43.1 (41.7-45.8)
0.85
Pneumothorax (%)
0 (0)
1 (4)
0.22
Survival (%)
28 (76)
18 (72)
0.74
Patient status at failure of SIMV
PIP (cmH2O)
0.92
Measured PEEP (cmH2O)
0.24
Ventilator rate
0.99
Ventilator MPaw (cmH2O)
0.74
pH
0.02
pCO2 (mmHg)
0.79
Base excess
<0.001
FiO2 (%)
0.45
Heart rate
0.76
Respiratory rate
0.22
BP MAP (mmHg)
0.08
Patient status at rescue†
Ventilator MPaw (cmH2O)
0.71
pH
<0.001
pCO2 (mmHg)
0.92
Base excess
<0.001
FiO2 (%)
0.22
Heart rate
0.47
BP MAP (mmHg)
0.048
†Values for both APRV and HFOV at the time of the second blood gas after rescue. PIP: peak inspiratory pressure; PEEP: positive end-expiratory pressure; pCO2: partial pressure of carbon dioxide; FiO2: fractional inspired oxygen; BP MAP: blood pressure mean arterial pressure; MPaw: mean airway pressure. Data expressed as median with interquartile range () or .
