Chitosan-Based Nanogel Enhances Chemotherapeutic Efficacy of 10-Hydroxycamptothecin against Human Breast Cancer Cells

Figure 4

Apoptotic cell populations were determined by FCM analyses with Annexin V-FITC and PI staining after coincubating 4T1 cells with PBS, free HCPT, or CS/HCPT for 24 h. The lower left (Q3), lower right (Q4), upper right (Q1), and upper left (Q2) quadrants in each panel indicated the populations of normal, early and late apoptotic, and apoptotic necrotic cells, respectively.

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