Research Article
An Efficient Herbal Approach for Treating Fungal Infection in Cervical Cancer Patients by Developing and Optimizing a Vaginal Suppository
Table 5
Design of experiment: optimization of the proportion of PEG 1500, PEG 6000, and Poloxamer 407 to prepare a curcumin vaginal suppository.
| | Formulations | PEG 1500 | PEG 6000 | Poloxamer 407 | Response 1 (hardness) | Response 2 (deformation time) min | Response 3 (% drug release) |
| | F1 | 40 | 43.1993 | 16.8007 | | | | | F2 | 33.4196 | 50.1743 | 16.4061 | | | | | F3 | 36.2578 | 40 | 23.7422 | | | | | F4 | 22.662 | 47.338 | 30 | | | | | F5 | 35 | 60 | 5 | | | | | F6 | 25.2137 | 56.5428 | 18.2435 | | | | | F7 | 17.2018 | 59.9957 | 22.8025 | | | | | F8 | 29.151 | 40.849 | 30 | | | | | F9 | 40 | 49.1694 | 10.8306 | | | | | F10 | 10 | 60 | 30 | | | | | F11 | 35 | 60 | 5 | | | | | F12 | 25.2137 | 56.5428 | 18.2435 | | | | | F13 | 25.2137 | 56.5428 | 18.2435 | | | | | F14 | 40 | 49.1694 | 10.8306 | | | | | F15 | 28.7641 | 47.7178 | 23.5181 | | | | | F16 | 22.662 | 47.338 | 30 | | | |
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