Controlled Release Bilayer Floating Effervescent and Noneffervescent Tablets Containing Levofloxacin and Famotidine

Table 8

The stability parameters of drug and dosage form in optimized selected formulations.

Parameters	F2	F5	F2	F5	F2	F5
Time (days)	After 30 days		After 60 days		After 90 days
Appearance	No changes	No change	No change	No change	No change	No change
Hardness (kg/cm^2)
Weight variation (mg)
Drug contents of levofloxacin (%)
Drug content of famotidine (%)
Floating lag time (second)
Total floating time (hours)
Swelling index (8 hours)
Erosion (%) (24 hours)