Bone Mineral Density in Cystic Fibrosis Patients with the CFTR I1234V Mutation in a Large Kindred Family Is Associated with Pancreatic Sufficiency

Table 2

Association of different factors between CF patients having normal and low vitamin D [25(OH)D].

Characteristics	CF patients with [25(OH)D] ≥30 (ng/mL) (𝑛=6)	CF patients with [25(OH)D] <30 (ng/mL) (𝑛=20)	𝑃 value
Age (years)	17.3±2.7	17.3±5.5	0.999
BMI	19.6±2.9	22.9±6.7	0.099
Gender (female)	3 (50%)	13 (65%)	0.644
Pseudomonas (+ive)	6 (100%)	10 (50%)	0.053
Time of exposure to the sun (<30 min per day)	3 (50%)	16 (80%)	0.293
Multivitamin (no)	2 (33.3%)	18 (90%)	0.013
Phosphorus (mmol/L)	1.3±0.17	1.4±0.20	0.504
Calcium level (mmol/L)	2.3±0.09	2.3±0.08	0.730
ALP (U/L)	80.7±23.0	122.9±53.2	0.011
Vitamin K levels (ng/L)	306.2±170.6	187.6±110.02	0.105
FEV1	75.3±26.2	85.2±8.9	0.403
L1–L4 BMD 𝑍 score	−0.58±1.41	−0.52±0.92	0.898
Total hip 𝑍 score	−0.13±1.21	−0.38±0.93	0.607
Total body 𝑍 score	−0.18±1.37	−0.22±0.83	0.944

BMI: body mass index.