Joint Degradation in a Monkey Model of Collagen-Induced Arthritis: Role of Cathepsin K Based on Biochemical Markers and Histological Evaluation

Figure 1

Joint swelling score, urinary cartilage marker (CTX-II/Cr), and bone turnover markers (CTX-I/Cr, NTX/Cr, and DPD/Cr).

(a)

(b)

(c)

(d)

(e)