International Journal of Rheumatology

Research Article

Autoimmune Regulator Gene Polymorphisms in Egyptian Systemic Lupus Erythematosus Patients: Preliminary Results

Table 2

Genotype and allele frequency of AIRE rs760426 in the lupus patients and control groups.


			Patients ()	Control ()	value	OR (95% CI)

Genotypes		GG, (%)	14 (14.1)	6 (4.9)	0.032
		AG, (%)	19 (19.2)	34 (27.6)
		AA, (%)	66 (66.7)	83 (67.5)
Models	Dominant	GG+AG, (%)	33 (33.3)	40 (32.5)	0.898	1 (0.6-1.8)
		AA, (%)	66 (66.7)	83 (67.5)
	Recessive	GG, (%)	14 (14.1)	6 (4.9)	0.017	3.2 (1.2-8.7)
		AA+AG, (%)	85 (85.9)	117 (95.1)
			Patients ()	Control ()
Alleles		G, (%)	47 (23.7)	46 (18.7)	0.195	1.4 (0.9-2.1)
		A, (%)	151 (76.3)	200 (81.3)

The comparisons were done using the Chi-square tests. After Bonferroni correction and logistic regression, the GG genotype was significantly more frequent in the patients group than the control group. : number, OR: odds ratio, CI: confidence interval.