Clinically Recognized Depression and Mental Health Treatment in a Single Center Cohort of Patients with Systemic Sclerosis
Table 3
Associations of SSc symptom burden and COVID-19 pandemic with CESD-R score.
Characteristic
CESD-R score
Beta coefficient (confidence interval)
Baseline dyspnea index
2.7 (1.5-3.8)
<0.01
UCLA SCTC GIT 2.0 total score
9.5 (4.8-14.1)
<0.01
UCLA SCTC GIT 2.0 reflux subscale
7.1 (2.5-11.8)
<0.01
UCLA SCTC GIT 2.0 distension/bloating
4.1 (1.4-6.8)
<0.01
UCLA SCTC GIT 2.0 diarrhea‡
6.3 (2.8-9.9)
<0.01
UCLA SCTC GIT 2.0 fecal soilage
5.0 (0.1-9.9)
0.05
UCLA SCTC GIT 2.0 constipation
2.6 (-0.7-5.9)
0.11
UCLA SCTC GIT 2.0 emotional well-being
6.9 (2.7-11.1)
<0.01
UCLA SCTC GIT 2.0 social function‡
10.2 (5.1-15.3)
<0.01
Raynaud’s condition score
0.8 (-0.1-1.7)
0.09
Modified Rodnan skin score
0.4 (0.1-0.6)
<0.01
Timepoint pre versus during COVID-19 pandemic
0.8 (-4.7-6.3)
0.76
Quantile regression models comparing median values, adjusted for age, gender, and disease duration since first non-Raynaud’s symptoms. 128 participants included in each model unless otherwise indicated. Missing dyspnea index data from 62 participants, . Missing data from 1 participant, . ‡Missing data from 2 participants, .