Comparison of IVF Outcomes between Minimal Stimulation and High-Dose Stimulation for Patients with Poor Ovarian Reserve

Table 1

Data comparison of minimal stimulation and high-dose stimulation protocols for low responders. Not significant results are denoted by NS.

	Minimum stimulation	High stimulation	value
Number of patients	70	71
Age (yr)	39.4 ± 3.2	39.2 ± 4.0	NS
Peak estradiol (pmol/L)	1580.8 ± 1141.2	5279.4 ± 3295.1	< 0.001
Gonadotropin total dose (IU)	1332.9 ± 435.7	5575.2 ± 1945.0	< 0.001
Antral follicle count	3.7 ± 1.0	4.5 ± 0.7	< 0.001
Number of oocytes retrieved	2.9 ± 1.5	3.5 ± 1.5	NS
Number of fertilized oocytes	1.5 ± 1.1	1.5 ± 1.2	NS
Cancellation rate	3/71 (4.2%)	4/79 (5.0%)	NS
Number of embryos transferred	1.8 ± 0.7	1.4 ± 1.2	NS
Clinical pregnancy rate/cycle	22/70 (31.4%)	9/71 (12.7%)	< 0.05
Live birth rate	15/70 (21.4%)	5/71 (7.0%)	< 0.05