Molecular Markers in Cutaneous Squamous Cell Carcinoma

Table 2

Clinicopathologic classification for cSCC*.

High risk behavior cSCC
Bowen’s disease with invasion
Adenosquamous carcinoma
cSCC in proliferating pilar tumor/cysts
Tricholemmal cysts
Epidermoid cysts
Desmoplastic cSCC
De novo cSCC
cSCC in chronic conditions
Ulcers, sinus tracts, burns
Osteomyelitis
Chronic inflammatory disorders
Radiation-induced cSCC
Indeterminate risk cSCC
Clear cell SCC
Signet ring cell
Papillary cSCC
Pigmented cSCC
Follicular cSCC
cSCC from benign adnexal cyst
Putative cSCC versus low grade cSCC
Keratoacanthoma (KA)
Not a bona fide cSCC
Low grade behavior
Giant KA,
Subungual KA
KA with Immunosuppression

*Modified Classification system from Cassarino et al. [24].