Second-Look Surgery for Colorectal Cancer: Revised Selection Factors and New Treatment Options for Greater Success

Figure 1

Ring diagram shows that hematogenous metastases and cancer seeding can occur in isolation or in combination with other sites of surgical treatment failure. High-density seeding at the resection site causes a layering of cancer; low-density seeding at a distance results in peritoneal carcinomatosis (reprinted from [18] with permission).