A Single Centre Analysis of Clinical Characteristics and Treatment of Endocrine Pancreatic Tumours

Table 1

WHO grading classification (2010) of pancreatic neuroendocrine tumours [22].

Low grade neuroendocrine tumour—G1	<2 mitoses/10 HPF and/or ≤2% Ki-67 proliferation index
Intermediate grade neuroendocrine tumour—G2	2–20 mitoses/10 HPF and/or 3%–20% Ki-67 proliferation index
High grade neuroendocrine carcinoma—G3	>20 mitoses/10 HPF and/or >20% Ki-67 proliferation index

Alternative Ki-67 cut-off value, 5% and 20%, between G1/G2 and G2/G3, respectively.