The Utility of SOX2 and AGR2 Biomarkers as Early Predictors of Tamoxifen Resistance in ER-Positive Breast Cancer Patients

Figure 2

A case of breast carcinoma in group 2 (tamoxifen resistant) with serum AGR2 level 116 ng/ml showed high SOX2 nuclear expression score 9 (a) and high AGR2 cytoplasmic positivity score 8 (b). A case of breast carcinoma in group 3 (tamoxifen resistant) with serum AGR2 level 224 ng/ml showed high SOX2 nuclear positivity score 12 (c) and high AGR2 cytoplasmic positivity score 12 (d) in malignant cells (X100).

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