Correlations between Endothelial Functions and ROS Detection in Diabetic Microvascular Wall: Early and Late Ascorbic Acid Supplementation

Table 2

Means ± S.E. of changes in DHR fluorescence intensities along the arterioles and venules. Values are means ± SE of each group, CON (𝑛=5), DM (𝑛=5), DM + AAday2 (𝑛=6), and DM + AA6wk (𝑛=5), calculated by using the equation of: % change of ROS-associated fluorescent intensity = (𝐼_1min−𝐼_base/𝐼_base)×100.

Group	% change of ROS in arteriolar wall	% change of ROS in venular wall
Control	34.08+15.62	38.31+18.71
DM	165.89+24.59 *	172.26±34.70^∗,a
DM + AAday2	32.86+14.56^#	49.59±21.26^#
DM + AA6wk	26.02+8.03^#	49.91±20.10^#

^∗𝑃<0.001, significant difference compared to control.
^#𝑃<0.001, significant difference compared to DM.
^a𝑃<0.05, significant difference between ROS contents in arteriolar wall and venular wall in DM group.