The Oxidative State of Chylomicron Remnants Influences Their Modulation of Human Monocyte Activation
Figure 1
Uptake of native, oxidised, and probucol treated CRLP by primary human blood monocytes. Monocytes were incubated with CRLP at 37°C for 24 h before cytospin fixation and oil Red O staining. (a) Representative images (captured at magnification ×40 and enlarged). (b) Volocity quantitation (pixel count analysis) from monocyte isolations. Approximately, 700 cells were examined for each condition. C15/C30 control equivalent volume to 15/30 μg/mL cholesterol, N15/N30, CRLP at 15/30 μg/mL cholesterol, O15/O30 oxCRLP at 15/30 μg/mL cholesterol, P15/P30 pCRLP at 15/30 μg/mL cholesterol. **, *** analysis by one-way ANOVA and Bonferroni’s posttest.
