Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs
Figure 7
L. amazonensis promastigotes treated with azasterols (a)-(b), and ER-119884 (c) showing alterations in the nuclear membrane ((a), arrowhead), in the Golgi complex ((b), arrowhead), and in the endoplasmic reticulum ((c), arrowhead). In the Figures 6(b) and 6(c), the presence of a multivesicular bodies and autophagosome-like structures (stars) could be related with a remodeling process of damaged organelle by autophagy. GC, Golgi complex; M, mitochondrion; N, nucleus. Bars, m.
