Utility of Serum Neopterin and Serum IL-2 Receptor Levels to Predict Absolute CD4 T Lymphocyte Count in HIV Infected Cases

Table 4

Measures of validity and roc curve area of neopterin and sIL-2R in relation to the CD4 cell count <200 cells/μL.

Measures of validity	S. neopterin (95% CI)	sIL-2R (95% CI)
Cutoff value	>25.1 nmol/L	>47.1 pM
Sensitivity	90.9; (95% CI: 70.8–98.9)	95.5; (95% CI: 77.2–99.9)
Specificity	67.4; (95% CI: 52.0–80.5)	60.9; (95% CI: 45.4–74.9)
Positive predictive value	86.4 (74.5–93.2)	92.3 (79.1–96.4)
Negative predictive values	70.0 (61.3–78.8)	58.7 (49.3–72.8)
ROC curve area	0.83 (0.71–0.90), 𝑃=0.0001	0.82 (0.71–0.90), 𝑃=0.0001