Current Perspectives on Treatment of Gram-Positive Infections in India: What Is the Way Forward?

Table 1

Gram positive organisms and recommended antimicrobial agents.

Organism	Recommended drugs	References
MSSA	Cefazolin, Cloxacillin	[11]
MRSA	Vancomycin, Daptomycin, Teicoplanin, Linezolid, Ceftaroline, Tigecycline	[15–17]
VISA, hVISA, VRSA	Combination of high-dose daptomycin with another antibiotic including gentamicin, rifampicin, linezolid, trimethoprim-sulfamethoxazole (TMP-SMX), or a β-lactam	[16]
VRE	Linezolid, High-dose ampicillin, daptomycin; nitrofurantoin, Fosfomycin (UTI); doxycycline, chloramphenicol, gentamicin, streptomycin (combination therapy)	[5, 28]
DRSP	Respiratory fluoroquinolones (moxifloxacin, Gemifloxacin, or levofloxacin), or a beta-lactam alone or in combination with a beta-lactamase inhibitor (high dose amoxicillin or amoxicillin-clavulanate) along with doxycycline	[41]