Research Article

Nasal Carriage by Staphylococcus aureus among Healthcare Workers and Students Attending a University Hospital in Southern Brazil: Prevalence, Phenotypic, and Molecular Characteristics

Table 3

Antimicrobial susceptibility of 139 Staphylococcus aureus isolated from nasal swab of healthcare workers and students attending the University Hospital of Londrina in southern Brazil.

AntimicrobialMSSA n = 99 (%)MRSA n = 40 (%)
SIRSIR

Penicillin13 (13.1)86 (86.9)40 (100.0)
Cefoxitin99 (100.0)25 (62.5)15 (37.5)
Oxacillin99 (100.0)28 (70.0)12 (30.0)
Chloramphenicol97 (98.0)2 (2.0)38 (95.0)1 (2.5)1 (2.5)
Ciprofloxacin90 (90.9)3 (3.0)6 (6.1)30 (75.0)6 (15.0)4 (10.0)
Clindamycin47 (47.5)2 (2.0)50 (50.5)8 (30.0)32 (80.0)
Erythromycin34 (34.3)7 (7.1)58 (58.6)4 (10.0)1 (2.5)35 (87.5)
Gentamicin91 (91.9)1 (1.0)7 (7.1)33 (82.5)2 (5.0)5 (12.5)
Linezolid99 (100.0)39 (97.5)1 (2.5)
Rifampicin98 (99.0)1 (1.0)40 (100.0)
Sulfamethoxazole/Trimethoprim87 (87.9)1 (1.0)11 (11.1)36 (90.0)1 (2.5)3 (7.5)
Tetracycline93 (93.9)1 (1.0)5 (5.1)36 (90.0)1 (2.5)3 (7.5)
Tigecycline98 (99.0)1 (1.0)40 (100.0)
Vancomycin99 (100.0)40 (100.0)

Antimicrobial susceptibility was determined by disk diffusion, except oxacillin and vancomycin that were determined by broth microdilution assay [23] and the agar-screen test [25], respectively. Disk diffusion and microdilution results were interpreted as recommended by CLSI [23] except tigecycline that was interpreted according to the EUCAST [24]. —: not detected; S: susceptible; I: intermediate; R: resistant.