Association of Toll-Like Receptor 2 (TLR2) Expression in Placenta and Intrauterine Exposure to Hepatitis B Virus

Table 1

Sample characteristics.

Characteristics	n = 59
Age (n (%))
<20 years old	5 (8.5)
20–35 years old	47 (79.7)
>35 years old	7 (11.9)
Parity (n (%))
Primigravida	27 (45.8)
Multigravida	32 (54.2)
Gestational age (n (%))
Preterm	8 (13.6)
Term	44 (74.6)
Postterm	7 (11.9)
Placental disorders (n (%))
Placenta previa	1 (1.7)
Placental abruption	0
Preeclampsia	2 (3.4)
Premature rupture of the membrane (n (%))	3 (5.1)
Fetal distress (n (%))	1 (1.7)
Delivery mode (n (%))
Vaginal delivery	47 (79.7)
Cesarean section	12 (20.3)
Maternal serological factors
HBsAg titer (n (%))
<1000 IU/ml	36 (61)
>1000 IU/ml	23 (39)
HBV DNA (n (%))
Negative	7 (11.8)
Positive	52 (88.1)
HBeAg (n (%))
Negative	43 (72.9)
Positive	16 (27.1)
Anti-HBs (n (%))
Negative	56 (94.9)
Positive	3 (5.1)
Anti-HBc (n (%))
Negative	21 (35.6)
Positive	38 (64.4)
Viral load (n (%))
<5.3 log 10 IU/ml	52 (88.1)
5.3 log 10 IU/ml	7 (11.8)
Intrauterine exposure of hepatitis B (n (%))
HBV DNA cord blood negative	18 (30.5)
HBV DNA cord blood positive	41 (69.5)
TLR2 expression in placenta tissue (n (%))
Score 0	5 (8.5)
Score 1	15 (25.4)
Score 2	15 (25.4)
Score 3	24 (40.7)