| | Topics | Most relevant keywords | Label | Frequency (percentage) |
| | Structural features | Gene, brucellosis, polymorphism, genotype, patient, isolate, control, genetic, strain, susceptibility | Gene | 107 (13.31%) | | Gene, brucella, omp, specie, usage, nucleotide, factor, pattern, strain, codon | Omp | 39 (4.85%) | | Brucella, assay, pcr, detection, gene, molecular, use, marker, sequence, specific | Marker | 158 (19.65%) | | Protein, brucella, omp, gene, melitensis, expression, recombinant, vaccine, cell, clone | Protein | 292 (36.32%) | | Gene, genome, sequence, analysis, identify, mutation, available, pathogen, genomic, bacterial | Genome | 208 (25.87) | | Overall | 804 (100%) | | Prevention | Brucella, test, sample, cattle, abortion, herd, melitensis, milk, strain, cow | Milk | 670 (9.78%) | | Disease, infection, cause, pathogen, brucella, animal, zoonotic, zoonosis, include, spe | Zoonotic | 949 (13.85%) | | Brucellosis, case, human, animal, control, high, disease, rate, incidence, livestock | Livestock | 1618 (23.61%) | | Property, biological, detection, laboratory, gene, agent, sequence, error, diagnosis, bioterrorism | Bioterrorism | 192 (2.80%) | | Available, brucellosis, vaccine, human, diagnosis, treatment, clinical, immunity, infection, chronic | Vaccine | 3424 (49.96%) | | Overall | 6853 (100%) | | Diagnosis | Die, ci, surveillance, por, brucellacapt, slaughterhouse, science, sat, al, unknown | Brucellacapt | 64 (1.40%) | | Test, brucellosis, diagnosis, elisa, serological, antibody, brucella, positive, sensitivity, serum | Elisa | 1539 (33.70%) | | Dog, antibody, brucella, canis, infection, pathogen, detect, und, pig, breed | Detect | 295 (6.46%) | | Infection, day, infect, strain, available, camel, month, organism, brucella, experimental | Organism | 143 (3.13%) | | Brucellosis, test, animal, sample, positive, prevalence, cattle, high, seroprevalence, brucella | Positive | 899 (19.68%) | | Sample, brucella, pcr, melitensis, positive, milk, isolate, isolation, blood, molecular | Pcr | 351 (7.63%) | | Patient, brucellosis, case, blood, culture, diagnosis, brucella, clinical, positive, treatment | Culture | 760 (16.64%) | | Brucellosis, case, infection, disease, fever, human, laboratory, cause, report, available | Laboratory | 516 (11.30%) | | Overall | 4567 (100%) | | Clinical symptoms | Colchicine, treatment, patient, therapy, fmf, attack, drug, month, treat, anti | Attack | 355 (5.64%) | | Brucellosis, patient, treatment, case, clinical, brucella, infection, diagnosis, year, child | Child | 1452 (23.06%) | | Lesion, cell, skin, inflammatory, immune, pathogenesis, inflammation, tissue, disease, syndrome | Lesion | 90 (1.43%) | | Case, report, brucellosis, present, cause, disease, diagnosis, involvement, brucella, rare | Disease | 1590 (25.25%) | | Patient, group, level, control, fmf, high, significantly, compare, acute, chronic | Acute | 638 (10.13%) | | Fever, woman, variant, msf, unknown_origin, pregnancy, mother, ocular, death, fuo | Fever | 78 (1.24%) | | Patient, fmf, disease, mutation, mefv, clinical, fever, child, gene, amyloidosis | Amyloidosis | 1224 (19.44%) | | Available, brucellosis, case, fever, chronic, etiology, child, comment, nea_familiar, fiebre_mediterr | Chronic | 869 (13.80%) | | Overall | 6296 (100%) | | Immunology | Host, pathogen, intracellular, cell, bacterial, bacteria, system, interaction, infection, mechanism | Intracellular | 174 (10.63%) | | Expression, gene, regulate, regulation, target, transcription, analysis, gntr, system, virb | Expression | 33 (2.02%) | | Brucella, strain, virulence, gene, mutant, melitensis, survival, abortion, macrophage, brucellosis | Macrophage | 589 (35.98%) | | Protein, response, role, brucella, cell, stress, pathway, play, bacterial, important | Pathway | 96 (5.86%) | | Mouse, abortion, infection, dependent, secretion, spleen, caspase, production, demonstrate, infect | Caspase | 93 (5.68%) | | Available, patient, peptide, study, iron, neutrophil, fmf, overall, disease, drug | Neutrophil | 53 (3.24%) | | Vaccine, brucella, infection, brucellosis, cell, response, induce, immune, melitensis, omp | Response | 258 (15.76%) | | Nitric_oxide, tumor, complementation, acid, reactive_oxygen, growth, catalyze, respiratory, vector, peritoneal | Nitric_oxide | 3 (0.18%) | | Cell, macrophage, brucella, infection, infect, abortion, induce, intracellular, apoptosis, expression | Apoptosis | 309 (18.88%) | | Phagosome, cathepsin, cross, particle, morphological, coat, barrier, lysosomal, intact, er_derive | Lysosomal | 2 (0.12%) | | Cytokine, rev, control, stimulate, sulglycotide, pylori, induction, production, significantly, dose | Cytokine | 27 (1.65%) | | Overall | 1637 (100%) | | Pathogenicity | Available, bacterial, brucella, community, treatment, detection, high, activity, effect, bacteria | Brucella | 264 (36.67%) | | Protein, bacterial, brucella, pathogen, bacteria, bind, show, enzyme, system, gene | Pathogen | 456 (63.33%) | | Overall | 720 (100%) | | Control | Cell, antibody, response, antigen, effect, blood, lymphocyte, level, immune, patient | Patient | 1372 (48.34%) | | Vaccine, brucella, group, brucellosis, mouse, response, infection, animal, immune, strain | Vaccine | 1466 (51.66%) | | Overall | 2838 (100%) | | Treatment | Culture, medium, growth, pylori, sample, blood, bacteria, brucella, condition, system | Culture | 523 (24.54%) | | Extract, activity, die, und, group, pdt, bacteria, study, catalase, fly | Bacteria | 183 (8.59%) | | Brucella, strain, melitensis, isolate, brucellosis, specie, available, abortion, identification, gene | Melitensis | 1107 (51.95%) | | Antibiotic, isolate, bacteria, strain, resistance, patient, activity, test, treatment, blood | Antibiotic | 318 (14.92%) | | Overall | 2131 (100%) |
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