Estimating Mental Health Conditions of Patients with Opioid Use Disorder

Figure 1

Topographic changes of δ powers in patients with opioid use disorder. (a) EEG traces of δ oscillations (1–4 Hz) representing 10 s activity from a healthy control (Top) and a patient with opioid use disorder. Horizontal scale bar, 1 s; vertical scale bar, 10 μV. (b) The δ powers were increased by >76% in the Cz, Pz, O1, and O2 electrodes. Open columns denote healthy controls and solid red columns indicate the opioid group. , vs. healthy controls determined by repeated measures ANOVA followed by post hoc Scheffe test. (c) The δ powers were increased by 51–75% in F3, F4, C3, Fz, C4, P3, P4, T3, T4, T5, and T6. Open columns denote the healthy control group, and solid green columns indicate the opioid group. , vs. healthy control determined by repeated measures ANOVA followed by post hoc Scheffe test. (d) The δ powers were increased by 11–50% in FP1, FP2, F7, and F8. Open columns denote the healthy control group, and solid brown columns indicate the opioid group. NS, vs. healthy control determined by repeated measures ANOVA. (e) Topographic correlation between increased θ oscillation (1–4 Hz) and electrodes on cortical scalps. The red area denotes high δ powers, the green for the medium δ powers, and the brown for the low δ powers.

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