Estimating Mental Health Conditions of Patients with Opioid Use Disorder

Figure 5

Topographic changes of γ powers in patients with opioid use disorder. (a) Examples of EEG traces representing 10 s γ oscillations from a healthy control (top) and a patient with opioid use disorder. Horizontal scale bar, 1 s; vertical scale bar, 2 μV. (b) The increase of γ powers was 51–75%, including F3, F4, Fz, and Cz. Open columns denote for the healthy control group, and solid green columns for the opioid group. NS, . vs. healthy controls determined by repeated measures ANOVA followed by post hoc Scheffe test. (c) The increase of β powers was 11–50% in FP1, FP2, C3, C4, F7, and F8. Open columns denote for the healthy control group, and solid brown columns for a low change in the opioid group. NS, vs. healthy control determined by repeated measures ANOVA. (d) The increase of β powers was <10% in P3, P4, T3, T4, T5, T6, and Pz. Open columns denote for the healthy control group, and zebra-striping columns for “no change” in the opioid group. NS, vs. healthy control determined by repeated measures ANOVA. (e) A tendency of reduction in β powers was found in O1 and O2. Open columns denote for the healthy control group, and solid blue columns for a reduction of γ oscillations in the opioid group. NS, vs. healthy control determined by repeated measures ANOVA. (f) Topographic correlation between γ oscillation (30–50 Hz) and electrodes on the scalp. The green areas denote for a medium increase of γ powers, the brown for the low γ powers, and the dark area for a low reduction of γ powers.

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